Abstract
Alcohol use disorder (AUD) represents a major global public health challenge, contributing to the loss of millions of lives worldwide. Despite its widespread prevalence, a substantial proportion of individuals affected by AUD do not receive appropriate or timely intervention. This significant treatment gap highlights the urgent need for expanded awareness, improved understanding, and the development of effective intervention strategies to address this critical health issue. Chronic alcohol consumption disrupts metabolic processes and adversely affects multiple organ systems, including the liver, brain, cardiovascular system, and gastrointestinal tract. Because alcohol is rapidly metabolized and widely distributed throughout the body, a comprehensive understanding of its metabolic pathways and of supportive interventions that may facilitate physiological recovery is essential. Furthermore, the complex interplay between alcohol metabolism, nutritional deficiencies, and natural or adjunctive therapeutic approaches presents valuable opportunities to address the multifactorial physiological challenges experienced by individuals with alcohol use disorder.
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