PriMera Scientific Surgical Research and Practice (ISSN: 2836-0028)

Literature Review

Volume 6 Issue 6

Natural Ingredients that can Support Various Areas of Autism in the Spectrum

Christina Rahm*

November 26, 2025

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Abstract

Autism Spectrum Disorder (ASD) is a neurological condition that affects individuals to varying degrees, often presenting challenges in social communication, restricted interests, and repetitive behaviors. The manifestation of symptoms can differ widely among individuals with autism, which may necessitate personalized and diverse therapeutic approaches. To date, there is no known cure for autism. However, therapy typically involves a combination of educational support, behavioral interventions, speech therapy, and pharmacological treatments aimed at managing associated symptoms. In recent years, growing attention has been directed toward incorporating vitamins, minerals, and bioactive compounds as complementary elements in traditional treatment protocols. These natural substances have shown potential in supporting various aspects of ASD, including cognitive function, behavior, mood regulation, and gastrointestinal health. By promoting cognitive, emotional, and physical well-being, natural ingredients may contribute to a more holistic approach to managing the challenges associated with Autism Spectrum Disorder.

References

  1. Abdellatif B., et al. “The promising role of probiotics in managing the altered gut in autism spectrum disorders”. International journal of molecular sciences 21.11 (2020): 4159.
  2. Alonso-Esteban Y., et al. “A systematic review on the impact of social confinement on people with autism spectrum disorder and their caregivers during the COVID-19 pandemic”. Brain sciences 11.11 (2021): 1389.  
  3. Barrios-Fernández S., et al. “A complementary sensory tool for children with autism spectrum disorders”. Children 7.11 (2020): 244.
  4. Barros A., et al. “Autism spectrum disorders and malocclusions: systematic review and meta-analyses”. Journal of Clinical Medicine 11.10 (2022): 2727.
  5. Bruni O., et al. “Changes in sleep patterns and disorders in children and adolescents with attention deficit hyperactivity disorders and autism spectrum disorders during the COVID-19 lockdown”. Brain Sciences 11.9 (2021): 1139.
  6. Byrska A., et al. “Patterns of food selectivity among children with autism spectrum disorder”. Journal of Clinical Medicine 12.17 (2023): 5469.
  7. Da Silva ACF, Barbosa TDS and Gavião MBD. “Parental perception of the oral health-related quality of life of children and adolescents with autism spectrum disorder (ASD)”. International journal of environmental research and public health 20.2 (2023): 1151.
  8. De Giani A., et al. “Effects of inulin-based prebiotics alone or in combination with probiotics on human gut microbiota and immune system markers: a randomized, double-blind, placebo-controlled study in healthy subjects”. Microorganisms 10.6 (2022): 1256.
  9. Deng L and Rattadilok P. “A sensor and machine learning-based sensory management recommendation system for children with autism spectrum disorders”. Sensors 22.15 (2022): 5803.
  10. Draudvilienė L., et al. “Two physiotherapy methods to improve the physical condition of children with autism spectrum disorder”. Children 11.7 (2024): 798.
  11. Folostina R., et al. “Mapping knowledge and training needs in teachers working with students with autism spectrum disorder: a comparative cross-sectional investigation”. Sustainability 14.5 (2022): 2986.
  12. Gątarek P and Kałużna-Czaplińska J. “Effect of Supplementation on Levels of Homovanillic and Vanillylmandelic Acids in Children with Autism Spectrum Disorders”. Metabolites 12.5 (2022): 423.
  13. Gevezova M., et al. “Association of NGF and mitochondrial respiration with autism spectrum disorder”. International Journal of Molecular Sciences 23.19 (2022): 11917.
  14. Harshe D., et al. “Remarks on Cross-disciplinary Appraisal of Knowledge and Beliefs Regarding the Diagnosis of Autism Spectrum Disorders in India: A Cross-sectional Survey”. Indian Journal of Psychological Medicine 42.4 (2020): 404-404.
  15. Khamis EM and AL Jabery MA. “Maternal Insights into Bullying Types and Effective Interventions for Children with Autism Spectrum Disorder in Jordanian Schools”. Societies 14.9 (2024): 157.
  16. Laterza L., et al. “Ecology and machine learning-based classification models of gut microbiota and inflammatory markers may evaluate the effects of probiotic supplementation in patients recently recovered from COVID-19”. International Journal of Molecular Sciences 24.7 (2023): 6623.
  17. Mazza JADS., et al. “Clinical and Family Implications of Cannabidiol (CBD)-Dominant Full-Spectrum Phytocannabinoid Extract in Children and Adolescents with Moderate to Severe Non-Syndromic Autism Spectrum Disorder (ASD): An Observational Study on Neurobehavioral Management”. Pharmaceuticals 17.6 (2024): 686.
  18. Nascimento PKDSB., et al. “Zinc Status and Autism Spectrum Disorder in Children and Adolescents: A Systematic Review”. Nutrients 15.16 (2023): 3663.
  19. O’Connor M., et al. “Autism spectrum disorder (ASD) presentations among referrals to a child and adolescent mental health service (CAMHS) inpatient unit in Ireland”. Clinical Child Psychology and Psychiatry 30.2 (2025): 279-293.
  20. Önal S, Sachadyn-Król M and Kostecka M. “A review of the nutritional approach and the role of dietary components in children with autism spectrum disorders in light of the latest scientific research”. Nutrients 15.23 (2023): 4852.
  21. Retuerto M., et al. “Analysis of Gut Bacterial and Fungal Microbiota in Children with Autism Spectrum Disorder and Their Non-Autistic Siblings”. Nutrients 16.17 (2024): 3004.
  22. Rum Y, Zachor DA and Dromi E. “Prosocial behaviors of children with autism spectrum disorder (ASD) during interactions with their typically developing siblings”. International Journal of Behavioral Development 45.4 (2021): 293-298.
  23. Sameea AA, Abd El-Wahab EW and Osman SO. “Risk of Autism Spectrum Disorder (ASD) Among 18 to 48 Month Old Children: A Multi-Center Study in Qatar”. Global Pediatric Health 11 (2024): 2333794X241284476.
  24. Sharma N and Andrade C. “Comments on Knowledge and Beliefs About Autism Spectrum Disorders in Indian Healthcare Professionals”. Indian Journal of Psychological Medicine 42.4 (2020): 405-405.
  25. Simonelli V., et al. “Internet Gaming Disorder in Children and Adolescents with Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder”. Brain Sciences 14.2 (2024): 154.  
  26. Sobieski M, Grata-Borkowska U and Bujnowska-Fedak MM. “Implementing an Early Detection Program for Autism Spectrum Disorders in the Polish Primary Healthcare Setting—Possible Obstacles and Experiences from Online ASD Screening”. Brain Sciences 14.4 (2024): 388.
  27. Suprunowicz M., et al. “Between Dysbiosis, Maternal Immune Activation and Autism: Is There a Common Pathway?”. Nutrients 16.4 (2024): 549.
  28. Tan WY, Hamzaid NH and Ibrahim N. “Parental Perceptions on the Importance of Nutrients for Children with Autism Spectrum Disorder (ASD) and the Coping Strategies: A Qualitative Study”. Nutrients 15.7 (2023): 1608.
  29. Van’t Hof M., et al. “Age at autism spectrum disorder diagnosis: A systematic review and meta-analysis from 2012 to 2019”. Autism 25.4 (2021): 862-873.
  30. Zhang M., et al. “Virtual reality technology as an educational and intervention tool for children with autism spectrum disorder: current perspectives and future directions”. Behavioral Sciences 12.5 (2022): 138.