PriMera Scientific Surgical Research and Practice (ISSN: 2836-0028)

Review Article

Volume 5 Issue 5

Current Cancer Treatments and the Challenges in Achieving a Cure

M Masilamani Selvam*, H Harikrishnan and MG Karthih

April 28, 2025

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Abstract

Cancer remains a leading cause of morbidity and mortality worldwide, despite continuous advancements in treatment. Current treatment modalities include chemotherapy, targeted therapy, immunotherapy, and precision medicine, each offering significant improvements in patient survival and quality of life. However, the ultimate goal of achieving a complete cure remains elusive due to several challenges. These include drug resistance, tumor heterogeneity, late-stage diagnosis, metastasis, severe side effects, and the high costs associated with innovative treatments. This article explores the existing cancer therapies, their effectiveness, and the key obstacles that hinder the development of a definitive cure. Ongoing research in nanotechnology, AI-driven drug discovery, and gene editing holds promise for more effective solutions. A multidisciplinary approach integrating early detection, personalized medicine, and accessible healthcare is essential for making meaningful progress in the fight against cancer.

Keywords: Cancer; therapy; challenges

References

  1. Cleanclay WD., et al. “Cancer Biology and Therapeutics: Navigating Recent Advances and Charting Future Directions”. Trop J Nat Prod Res 7.12 (2023): 5377-5402.
  2. Ramos R., et al. “Lung Cancer Therapy: The Role of Personalized Medicine”. Cancers 17 (2025): 725.
  3. Raghani NR., et al. “Revolutionizing cancer treatment: comprehensive insights into immunotherapeutic strategies”. Med Oncol 41 (2024) 51.
  4. Jin H, Wang L and Bernards R. “Rational combinations of targeted cancer therapies: background, advances and challenges”. Nat Rev Drug Discov 22 (2023): 213-234.
  5. Zafar A., et al. “Revolutionizing cancer care strategies: immunotherapy, gene therapy, and molecular targeted therapy”. Mol Biol Rep 51 (2024): 219.
  6. Fountzilas E., et al. “Clinical trial design in the era of precision medicine”. Genome Med 14 (2022): 101.
  7. Guo L., et al. “Breast cancer heterogeneity and its implication in personalized precision therapy”. Exp Hematol Oncol 12 (2023): 3.
  8. Li Y., et al. “Invasion and metastasis in cancer: molecular insights and therapeutic targets”. Sig Transduct Target Ther 10 (2025): 57.