PriMera Scientific Surgical Research and Practice (ISSN: 2836-0028)

Review Article

Volume 4 Issue 2

Validation of Quantitative Electroencephalogram (qEEG) Normative Databases

Jonathan RT Lakey* and Slav Danev

July 12, 2024

DOI : 10.56831/PSSRP-04-120

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Abstract

Quantitative electroencephalogram (qEEG) helps a) characterize normal versus disease, developmental and neurocognitive states as well as b) in diagnosis and prognosis enabling a clinician to determine via statistics if a client/subject is, i) within a reference normal population, ii) how best to customize treatment based on the client’s/subject’s qEEG results and iii) if a client/subject is responding positively to treatment. However constructing of qEEG normative databases for use in both research and clinical settings has proved challenging over the last 61 years due to methodological issues such as, i) determining who makes up the “normal” study population and ii) lack of standardized procedures when acquiring, measuring, analyzing, and interpreting resting state or active task EEG data. This review focuses on a) the many challenges/milestones the field had to overcome, b) standards to be followed when constructing and validating a normative databases c) commonly used peer-reviewed normative databases, and d) an illustrated step-by-step guide to qEEG normative database validation and comparison.

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