PriMera Scientific Surgical Research and Practice (ISSN: 2836-0028)

Case Study

Volume 2 Issue 3

An Atypical Case of High Prostate Specific Antigen in a False-Positive Case of Benign Prostatic Hypertrophy/Hyperplasia: A Case Study

Daniel David Otobo*, Johnson Yonni, Daniel Mesak, Jacob Adefila, Doreen Ihuka-Otele, Osas Idehen, Manasseh Tsavsar and Tochukwu Ebuka

August 11, 2023

DOI : 10.56831/PSSRP-02-056


Background: Prostate-specific antigen (PSA) testing has long been used as a screening tool for prostate cancer. However, it is not without its limitations. In some cases, men may receive a false-positive PSA result, which can lead to unnecessary anxiety and concerns about their risk of developing cancer.

Aim: This study aims to reveal and discuss the case of a patient with a false-positive PSA value of 100 ng/mL.

Discussion/Conclusion: Depending on PSA assays as an all-seeing eye in detecting and screening for Prostate Cancers (PCa), may not be completely reliable. Studies have found its sensitivity and specificity questionable. Although current studies have put the borderline values between 4ng/mL and 10ng/mL, many studies have found PCa biopsy-positive cases at values lower than 4ng/mL and negative cases at values greater than 10ng/mL. Nevertheless, the concept of overtreating and overdiagnosis was also touched on.


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