PriMera Scientific Medicine and Public Health (ISSN: 2833-5627)

Review Article

Volume 5 Issue 3

Correlation of anti-thyroperoxidase (Anti-TPO) with Anxiety and Depression in Patients with Autoimmune Thyroid Diseases in Kosovo

Valon Morina*, Dhurata Kastrati and Drilona Berisha

September 03, 2024

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Abstract

Thyroid hormones are regulators of various physiological processes within the human body, which become particularly evident in case of imbalance. Autoimmune thyroid disease affects about 10% of the population worldwide with an increased incidence in women (Hayter, 2012). The aim is to analyze the reference values of thyroid anti-peroxidase (anti-TPO) and evaluate the relationship between mood disorders such as anxiety, depression and autoimmune thyroid diseases. The correlation of autoimmune thyroid disease with anxiety disorders is significant because it is also the most prevalent mental health problem in women (Rector, 2006), followed by depression. The research was carried out in digestive health institutions in the municipality of Pristina, namely in the American-Kosovar AmeriKos polyclinic and the Vital Group clinic in Pristina with a total sample of N-80 female respondents, of which 40 patients with a positive result of Anti-TPO and 40 with a negative Anti-TPO result. The research was carried out based on the qualitative method and the instruments that were used consisted of questionnaires related to anxiety and depression that were determined using the HADS assessment (Zigmond, 1983). The research results show that anxiety and depression have a significant negative strong correlation with people with autoimmune thyroid disease: (alpha = 0.05, P= .002), A -0.4398 and D -0.4608. Based on this research, we can conclude that individuals in the community with autoimmune thyroid disease with positive Anti-TPO may be at high risk for mood disorders, depression and anxiety, the basic factors in normal functioning in life.

Keywords: Hypothyroidism; Autoimmune disease; Anti-peroxidase; anxiety disorders; Autoimmune thyroiditis; Depression; Gills; Hashimoto's thyroiditis

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