PriMera Scientific Medicine and Public Health (ISSN: 2833-5627)

Research Article

Volume 5 Issue 3

Monitoring of Patients with Covid 19 based on Certain Biochemical Parameters

Ndiaye A*, Gueye MM, Samba A, Thiam S, Soumah IY, Diedhiou F, Coly NF, Cisse F and Diallo F

September 03, 2024

DOI : 10.56831/PSMPH-05-163

Abstract

Introduction: In December 2019, in the city of Wuhan, Hubei province, Covid 19 appeared and spread rapidly around the world. This syndrome is associated with failure and damage to several organs; or even a disruption of cellular metabolism.

Materials and Methods: This is a prospective, descriptive and analytical study of patients infected with SARS-Cov2. For each patient, the determination of certain biochemical parameters (albumin, creatinine, urea, sodium, potassium) was carried out with the ARCHITECT plus Ci4100 PLC.

Results: Our study population consisted of 153 subjects with covid-19 with a mean age of 55 ± 19 years. Male sex represented 53.8% of the study population, with a sex ratio of 1.15. We noted that 45.1% of patients had a severe form of the disease and 50.3% had a comorbidity. The disturbances noted are hypoalbuminemia, hypercreatininemia, hyperuremia, hyponatremia and hyperkalemia.

Conclusion: The incidence of death was significantly high in patients with disruption of biochemical parameters.

References

  1. World Health Organization. Coronavirus disease 2019 (COVID-19): situation report 72 (2020).
  2. V Bonny., et al. “COVID-19: pathophysiology of a disease with many faces”. Rev. Médecine Interne, vol. 41, no. 6, (2020): 375-389.
  3. R Mahieu and V Dubée. “Clinical and epidemiological characteristics of Covid-19”. Actual. Pharm (2020): S0515370020302974.
  4. ML Yeung., et al. “Soluble ACE2-mediated cell entry of SARS-CoV-2 via interaction with proteins related to the renin-angiotensin system”. Cell 184.8 (2021): 2212-2228.e12.
  5. Na Zhu., et al. “A Novel Coronavirus from Patients with Pneumonia in China, 2019”. NEJM”. 382 (2020): 727-733.
  6. I Jamai Amir., et al. “Covid-19: Virology, Epidemiology, and Biological Diagnostics”. Option/Bio 31.619 (2021): 15-20.
  7. Ketfi A., et al. “Clinical, biological and radiological profile of Algerian patients hospitalized for COVID-19: preliminary data”. The Pan African Medical Journal (2020).
  8. Y Michalakis, MT Sofonea and S Alizon. “Could the sex-specific effects of COVID-19 in France be explained by comorbidities?”.
  9. M Camara. “Epidemiological profile of covid - 19 cases in commune 6 of the Bamako district”. Thesis, USTTB (2021).
  10. FA Faye., et al. “Setting up an epidemic treatment center (ETC) for Covid-19 in an Internal Medicine department; lessons learned”. Rev. Afr. Médecine Interne 8.1‑2 (2021).
  11. Y Cheng., et al. “Kidney disease is associated with in-hospital death of patients with COVID-19”. Kidney Int 97.5 (2020): 829‑838.
  12. KH Chu., et al. “Acute renal impairment in coronavirus-associated severe acute respiratory syndrome”. Kidney Int 67.2 (2005): 698‑705.
  13. H Ali., et al. “Survival rate in acute kidney injury superimposed COVID-19 patients: a systematic review and meta-analysis”. Ren. Fail 42.1 (2020): 393‑397.
  14. N Kin and A Vabret. “Human coronavirus infections”. Rev. Francoph. Lab 487 (2016): 25‑33.
  15. G Wong., et al. “MERS, SARS, and Ebola: The Role of Super-Spreaders in Infectious Disease”. Cell Host Microbe 18.4 (2015): 398-401.