Predictors of Poor Prognosis during the 2015 Meningitis Epidemic at Niamey National Hospital
Gado Amadou Mahamadou, Boulama Malam Mamadou, Amadou Mahamane Laouali Harouna, Akilou Abdoulsalam, Mamane Daou, Ayouba Ismael Tinni, Moussa Sahada Salèye, Yacouba Nouhou, Hanki Yahayé and Adehossi Eric
January 28, 2023
Abstract
The countries of the Peysonnia belt are paying a heavy price for bacterial meningitis. Morbidity and mortality of bacterial meningitis is linked to certain factors.
It is a descriptive and analytical prospective study over a period of two months from April 15 to June 15, 2015 in subjects admitted for suspected meningitis at the National Hospital of Niamey. Identifying predictors of poor prognosis during this outbreak is our goal.
One hundred and five patients were enrolled. The majority were young. Signs of severity were coma (22.9%), seizures (12.4%), signs of focus (9.5%), shock (7.5%). Delay in management and hyperproteinrachia have also been identified as poor prognostic factors. Sequelae were balance disorders (n=20; 19%), hearing loss (n=7; 6.6%), purpura fulminans (n=13; 12.4%). There were 12 deaths or 11.4% of which 11 comas (91.66%), 2 convulsions (16.66%), 1 purpura fulminans (8.3%), 6 shock (50%), 5 signs of focus (41.66%), 8 of these patients (66.66%) came 3 days after the onset of signs.
Poor prognosis factors were related to brain damage, shock and delayed management. Improving Niger's health system will reduce them.
Keywords: bacterial meningitis; poor prognostic factors; Niamey; Niger
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