Research Article
Volume 2 Issue 1
Diarra Luka*, Marico M, Diarra S, Sangaré A, Diepkile A, Sanogo A, Doumbia S, Bagayoko M, Dembélé D, Doumbia T, Coulibaly S, Konaté C, Dissa M and Ouologuem I
December 23, 2022
DOI : 10.56831/PSMPH-01-029
Abstract
The objective of this work was to describe the epidemiological and bacteriological aspects of urinary tract infection in Sikasso hospital. This descriptive prospective cross-sectional study took place from February to August 2022 in the laboratory of Sikasso hospital. The identification of the bacteria was made from cultural, biochemical (Api 20E gallery) and antigenic characters. Antibiotic resistance was performed using the disc technique in agar medium and interpretation was made according to the recommendations of the antibiogram committee of the French microbiology society. We practiced 448 uine cytobacteriological examinations of which 61 met the urinary tract infection criteria, ie a prevalence of 13.62%. Gram-negative bacteria accounted for 98.36% of isolates with a predominance of E. coli 75.40%, followed by Klebsiella pneumonia 18.03%. The age group 60 and over in males was the most affected with 64.86% (p: 0.0001) of cases. A significant relationship was found for age (p: 0.0001), gender (p: 0.04) and the urinary tract infection. Concerning sensitivity to antibiotics E. coli opposed a resistance of 92.50% to aminopenicillins, 82.93% to cotrimoxazole, 76.09% to 3rd generation cephalosporins and 65.22% to ciprofloxacin. The resistance mechanism by extended-spectrum betalactamase production was observed in 47.83% of E. coli strains. At the end of this study, the hospital prevalence of urinary tract infection is estimated at 13.64% with Escherichia coli and Klebsiella pneumoniae as the majority microorganisms.
Keywords: Epidemiology; bacteriology; urinary tract infection; Sikasso; Mali