Research Article
Volume 1 Issue 3
Stella Kuyet Udu, Moses Edache Entonu*, Ekpa Emmanuel, Bulus Timothy and Alpha Kargbo
November 12, 2022
Abstract
Antioxidants are widely distributed in plants that are either used as food or medicine. These natural antioxidants, especially carotenoids, and polyphenols exhibit a wide range of biological effects which include; anti-inflammatory, anti-aging, anti-atherosclerosis and anticancer. Extraction and proper assessment of antioxidants from plants are crucial to explore the potential antioxidant sources and promote the application in functional foods, additives and pharmaceutical. The in-vitro antioxidant and ameliorating effect of butanol extract of Turmeric (C. longa) on osmotic-induced haemolysis was examined. Various experimental model including iron (III) reducing capacity, total antioxidant capacity, DPPH scavenging activity and in-vitro inhibition of osmotic-induced haemolysis were used for the characterization of antioxidant activity and ameliorating effect of the extract. The extract showed various degree of efficacy in each assay in dosed depended manner. In addition, at concentration of 1000µg/ml, the DPPH radical scavenging activity of the extract was found to compare well with that of the standard compound of ascorbic and gallic acids. From the obtained results, C. longa may be considered to be a source of antioxidant which can prevent oxidative stress.
Keywords: Turmeric; In-vitro; Antioxidant; Ameliorative; Haemolysis; Radicals; Scavenging